Sirinart Kumfu Selected Research

Left Ventricular Dysfunction

3/2018	Combined iron chelator and T-type calcium channel blocker exerts greater efficacy on cardioprotection than monotherapy in iron-overload thalassemic mice.
1/2018	Estrogen deprivation aggravates cardiometabolic dysfunction in obese-insulin resistant rats through the impairment of cardiac mitochondrial dynamics.
1/2016	Effects of Iron Overload on Cardiac Calcium Regulation: Translational Insights Into Mechanisms and Management of a Global Epidemic.
1/2016	Combined Iron Chelator and Antioxidant Exerted Greater Efficacy on Cardioprotection Than Monotherapy in Iron-Overloaded Rats.

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Sirinart Kumfu Research Topics

Disease

25	Iron Overload 03/2024 - 02/2011
16	Mitochondrial Diseases (Mitochondrial Disease) 11/2023 - 05/2011
12	Cardiomyopathies (Cardiomyopathy) 11/2023 - 02/2011
6	Inflammation (Inflammations) 10/2022 - 02/2016
6	Heart Failure 11/2019 - 02/2011
5	Cognitive Dysfunction 01/2023 - 06/2015
5	Thalassemia 10/2022 - 02/2011
4	Left Ventricular Dysfunction 03/2018 - 01/2016
4	Insulin Resistance 01/2018 - 01/2015
4	Fibrosis (Cirrhosis) 02/2016 - 01/2013
3	Obesity 07/2022 - 01/2015
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2015
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 01/2015
3	Anemia 01/2022 - 01/2017
3	Reperfusion Injury 01/2018 - 05/2011
2	Gestational Diabetes (Gestational Diabetes Mellitus) 04/2022 - 05/2018
2	Hemochromatosis (Bronze Diabetes) 01/2022 - 01/2020
2	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 01/2018
2	Ischemia 01/2018 - 12/2014
2	Infarction (Infarctions) 12/2014 - 10/2013
2	Myocardial Infarction 10/2013 - 01/2013
1	Dysbiosis 10/2022
1	Heart Diseases (Heart Disease) 07/2022
1	Fetal Weight 04/2022
1	Birth Weight (Birth Weights) 04/2022
1	Vascular System Injuries 01/2022
1	Thrombosis (Thrombus) 01/2022
1	Infections 11/2021
1	Neuroinflammatory Diseases 01/2021
1	Ovarian Neoplasms (Ovarian Cancer) 01/2021
1	Azotemia 01/2021
1	Proteinuria 01/2021
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2019
1	Neoplasms (Cancer) 08/2018
1	Chronic Pain 06/2018
1	Pain (Aches) 06/2018
1	beta-Thalassemia (Cooley's Anemia) 01/2017

Drug/Important Bio-Agent (IBA)

24	IronIBA 11/2023 - 02/2011
8	Chelating AgentsIBA 10/2022 - 01/2016
7	Transferrin (beta 2 Transferrin)IBA 01/2022 - 06/2012
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2016
4	AntioxidantsIBA 03/2024 - 01/2016
4	DeferiproneIBA 10/2022 - 01/2016
4	T-Type Calcium Channels (T-Type Calcium Channel)IBA 01/2022 - 01/2017
4	Insulin (Novolin)FDA Link 01/2018 - 01/2015
3	Deferoxamine (Desferal)FDA LinkGeneric 11/2023 - 01/2016
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 05/2011
3	CytokinesIBA 01/2022 - 02/2016
3	Isoflurophate (DFP)FDA Link 03/2018 - 01/2016
3	Estrogens (Estrogen)FDA Link 01/2018 - 01/2015
3	CollagenIBA 02/2016 - 01/2013
2	Metformin (Glucophage)FDA LinkGeneric 04/2022 - 06/2015
2	Lipocalin-2IBA 01/2022 - 01/2021
2	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 01/2022 - 11/2017
2	hemoglobin Bart'sIBA 01/2022 - 01/2021
2	VildagliptinIBA 01/2019 - 06/2015
2	Biomarkers (Surrogate Marker)IBA 08/2018 - 05/2018
2	humaninIBA 01/2018 - 01/2016
2	L-Type Calcium Channels (Dihydropyridine Receptor)IBA 11/2017 - 06/2012
2	Iron Chelating AgentsIBA 11/2017 - 01/2015
2	efonidipineIBA 03/2017 - 04/2016
2	Cysteine (L-Cysteine)FDA Link 01/2017 - 01/2016
2	CalciumIBA 01/2017 - 01/2016
2	Deferasirox FDA Link 01/2017 - 01/2016
2	salicylhydroxamic acid (SHAM)IBA 01/2016 - 12/2014
2	Malondialdehyde (Propanedial)IBA 01/2016 - 06/2012
1	necrostatin-1IBA 11/2023
1	Dextrans (Dextran)FDA Link 11/2023
1	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketoneIBA 11/2023
1	ferrostatin-1IBA 11/2023
1	Volatile Fatty AcidsIBA 10/2022
1	trimethyloxamine (trimethylamine N-oxide)IBA 10/2022
1	Peptides (Polypeptides)IBA 07/2022
1	Particulate MatterIBA 01/2022
1	Environmental Pollutants (Pollutants, Environmental)IBA 01/2022
1	Non-Receptor Type 6 Protein Tyrosine PhosphataseIBA 01/2022
1	Thrombin FDA Link 01/2022
1	Bevacizumab (Avastin)FDA Link 01/2021
1	Carboplatin (JM8)FDA LinkGeneric 01/2021
1	Palmitic Acid (Hexadecanoic Acid)IBA 01/2021
1	PlatinumIBA 01/2021
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2021
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2019
1	dapagliflozinIBA 01/2019
1	SodiumIBA 01/2019
1	Hydrocortisone (Cortisol)FDA LinkGeneric 06/2018
1	Indicators and Reagents (Reagents)IBA 06/2018
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2018
1	Hemoglobins (Hemoglobin)IBA 01/2017
1	Calcium-Transporting ATPases (Ca2+ ATPase)IBA 01/2017
1	beta-Globins (beta Globin)IBA 01/2017
1	metal transporting protein 1 (ferroportin)IBA 04/2016
1	HepcidinsIBA 04/2016
1	Matrix Metalloproteinases (MMPs)IBA 02/2016

Therapy/Procedure

6	Therapeutics 01/2021 - 12/2012
3	Blood Transfusion (Blood Transfusions) 01/2022 - 02/2011
3	Vagus Nerve Stimulation 02/2016 - 12/2014
1	Drug Therapy (Chemotherapy) 01/2021
1	Tai Ji (Tai Chi Chuan) 01/2018